| Date | Opponents | Type | Res/KO | Venue |
|---|---|---|---|---|
| Sat 10 Aug 1968 | Huddersfield Town | League | D 0-0 | Leeds Road |
| Tue 13 Aug 1968 | Carlisle United | League | D 0-0 | Brunton Park |
| Sat 17 Aug 1968 | MIDDLESBROUGH | League | W 3-0 | Fratton Park |
| Wed 21 Aug 1968 | BLACKBURN ROVERS | League | L 0-1 | Fratton Park |
| Sat 24 Aug 1968 | Birmingham City | League | L 2-5 | St. Andrews |
| Mon 26 Aug 1968 | Preston North End | League | D 0-0 | Deepdale |
| Sat 31 Aug 1968 | CARDIFF CITY | League | L 1-3 | Fratton Park |
| Sat 07 Sep 1968 | Charlton Athletic | League | L 1-2 | The Valley |
| Fri 13 Sep 1968 | BURY | League | L 1-2 | Fratton Park |
| Sat 21 Sep 1968 | Norwich City | League | W 1-0 | Carrow Road |
| Sat 28 Sep 1968 | CRYSTAL PALACE | League | D 3-3 | Fratton Park |
| Sat 05 Oct 1968 | OXFORD UNITED | League | W 3-0 | Fratton Park |
| Wed 09 Oct 1968 | PRESTON NORTH END | League | D 1-1 | Fratton Park |
| Sat 12 Oct 1968 | Blackpool | League | D 1-1 | Bloomfield Road |
| Sat 19 Oct 1968 | DERBY COUNTY | League | L 0-1 | Fratton Park |
| Sat 26 Oct 1968 | Bristol City | League | D 2-2 | Ashton Gate |
| Sat 02 Nov 1968 | SHEFFIELD UNITED | League | W 2-1 | Fratton Park |
| Sat 09 Nov 1968 | Fulham | League | D 2-2 | Craven Cottage |
| Sat 16 Nov 1968 | ASTON VILLA | League | W 2-0 | Fratton Park |
| Sat 23 Nov 1968 | Hull City | League | D 2-2 | Boothferry Park |
| Sat 30 Nov 1968 | MILLWALL | League | W 3-0 | Fratton Park |
| Sat 07 Dec 1968 | Bolton Wanderers | League | L 0-1 | Burnden Park |
| Sat 14 Dec 1968 | BLACKPOOL | League | W 1-0 | Fratton Park |
| Sat 21 Dec 1968 | Derby County | League | L 1-2 | Baseball Ground |
| Sat 28 Dec 1968 | BRISTOL CITY | League | D 1-1 | Fratton Park |
| Sat 11 Jan 1969 | Sheffield United | League | L 0-2 | Bramall Lane |
| Sat 18 Jan 1969 | FULHAM | League | W 3-1 | Fratton Park |
| Sat 01 Feb 1969 | Aston Villa | League | L 0-2 | Villa Park |
| Sat 08 Feb 1969 | HULL CITY | League | W 1-0 | Fratton Park |
| Sat 15 Feb 1969 | Millwall | League | D 0-0 | The Den (old) |
| Sat 22 Feb 1969 | BOLTON WANDERERS | League | D 2-2 | Fratton Park |
| Sat 01 Mar 1969 | HUDDERSFIELD TOWN | League | L 1-2 | Fratton Park |
| Wed 05 Mar 1969 | Oxford United | League | L 1-3 | Manor Ground |
| Sat 08 Mar 1969 | Middlesbrough | League | L 0-1 | Ayresome Park |
| Sat 15 Mar 1969 | BIRMINGHAM CITY | League | D 0-0 | Fratton Park |
| Fri 21 Mar 1969 | Cardiff City | League | D 2-2 | Ninian Park |
| Sat 29 Mar 1969 | CHARLTON ATHLETIC | League | W 4-1 | Fratton Park |
| Sat 05 Apr 1969 | Crystal Palace | League | L 1-3 | Selhurst Park |
| Mon 07 Apr 1969 | Blackburn Rovers | League | L 1-3 | Ewood Park |
| Wed 09 Apr 1969 | CARLISLE UNITED | League | W 2-1 | Fratton Park |
| Sat 12 Apr 1969 | NORWICH CITY | League | W 5-2 | Fratton Park |
| Fri 18 Apr 1969 | Bury | League | L 2-3 | Gigg Lane |