| Date | Opponents | Comp | Res | Venue |
|---|---|---|---|---|
| Wed 19 Aug 1953 | Liverpool | League | L 1-3 | Anfield |
| Sat 22 Aug 1953 | SHEFFIELD UNITED | League | L 3-4 | Fratton Park |
| Tue 25 Aug 1953 | Chelsea | League | L 3-4 | Stamford Bridge |
| Sat 29 Aug 1953 | Huddersfield Town | League | L 1-5 | Leeds Road |
| Wed 02 Sep 1953 | CHELSEA | League | W 3-2 | Fratton Park |
| Sat 05 Sep 1953 | ASTON VILLA | League | W 2-1 | Fratton Park |
| Mon 07 Sep 1953 | Blackpool | League | D 1-1 | Bloomfield Road |
| Sat 12 Sep 1953 | Wolverhampton Wanderers | League | L 3-4 | Molineux |
| Wed 16 Sep 1953 | BLACKPOOL | League | D 4-4 | Fratton Park |
| Sat 19 Sep 1953 | SUNDERLAND | League | W 4-1 | Fratton Park |
| Sat 26 Sep 1953 | Manchester City | League | L 1-2 | Maine Road |
| Sat 03 Oct 1953 | CARDIFF CITY | League | D 1-1 | Fratton Park |
| Sat 10 Oct 1953 | Burnley | League | L 0-1 | Turf Moor |
| Sat 17 Oct 1953 | CHARLTON ATHLETIC | League | W 3-1 | Fratton Park |
| Sat 24 Oct 1953 | Sheffield Wednesday | League | D 4-4 | Hillsborough |
| Sat 31 Oct 1953 | MIDDLESBROUGH | League | L 0-2 | Fratton Park |
| Sat 07 Nov 1953 | Bolton Wanderers | League | L 1-6 | Burnden Park |
| Sat 14 Nov 1953 | PRESTON NORTH END | League | L 1-3 | Fratton Park |
| Sat 21 Nov 1953 | Newcastle United | League | D 1-1 | St. James Park |
| Sat 28 Nov 1953 | MANCHESTER UNITED | League | D 1-1 | Fratton Park |
| Sat 05 Dec 1953 | West Bromwich Albion | League | W 3-2 | The Hawthorns |
| Sat 12 Dec 1953 | LIVERPOOL | League | W 5-1 | Fratton Park |
| Sat 19 Dec 1953 | Sheffield United | League | L 1-3 | Bramall Lane |
| Fri 25 Dec 1953 | Tottenham Hotspur | League | D 1-1 | White Hart Lane |
| Sat 26 Dec 1953 | TOTTENHAM HOTSPUR | League | D 1-1 | Fratton Park |
| Sat 02 Jan 1954 | HUDDERSFIELD TOWN | League | W 5-2 | Fratton Park |
| Sat 16 Jan 1954 | Aston Villa | League | D 1-1 | Villa Park |
| Sat 23 Jan 1954 | WOLVERHAMPTON WANDERERS | League | W 2-0 | Fratton Park |
| Sat 06 Feb 1954 | Sunderland | League | L 1-3 | Roker Park |
| Sat 13 Feb 1954 | MANCHESTER CITY | League | W 4-1 | Fratton Park |
| Sat 27 Feb 1954 | BURNLEY | League | W 3-2 | Fratton Park |
| Wed 03 Mar 1954 | Cardiff City | League | L 2-3 | Ninian Park |
| Sat 06 Mar 1954 | Charlton Athletic | League | L 1-3 | The Valley |
| Sat 20 Mar 1954 | Middlesbrough | League | D 2-2 | Ayresome Park |
| Sat 27 Mar 1954 | BOLTON WANDERERS | League | W 3-2 | Fratton Park |
| Sat 03 Apr 1954 | Preston North End | League | L 0-4 | Deepdale |
| Wed 07 Apr 1954 | SHEFFIELD WEDNESDAY | League | W 2-1 | Fratton Park |
| Sat 10 Apr 1954 | NEWCASTLE UNITED | League | W 2-0 | Fratton Park |
| Fri 16 Apr 1954 | Arsenal | League | L 0-3 | Highbury |
| Sat 17 Apr 1954 | Manchester United | League | L 0-2 | Old Trafford |
| Mon 19 Apr 1954 | ARSENAL | League | D 1-1 | Fratton Park |
| Sat 24 Apr 1954 | WEST BROMWICH ALBION | League | W 3-0 | Fratton Park |
