| Date | Opponents | Comp | Res | Venue |
|---|---|---|---|---|
| Sat 20 Aug 1955 | Huddersfield Town | League | L 0-1 | Leeds Road |
| Wed 24 Aug 1955 | WOLVERHAMPTON WANDERERS | League | W 2-1 | Fratton Park |
| Sat 27 Aug 1955 | BLACKPOOL | League | D 3-3 | Fratton Park |
| Wed 31 Aug 1955 | Wolverhampton Wanderers | League | L 1-3 | Molineux |
| Sat 03 Sep 1955 | Chelsea | League | W 5-1 | Stamford Bridge |
| Sat 10 Sep 1955 | BOLTON WANDERERS | League | D 3-3 | Fratton Park |
| Sat 17 Sep 1955 | Arsenal | League | W 3-1 | Highbury |
| Sat 24 Sep 1955 | EVERTON | League | W 1-0 | Fratton Park |
| Sat 01 Oct 1955 | SUNDERLAND | League | W 2-1 | Fratton Park |
| Sat 08 Oct 1955 | Newcastle United | League | L 1-2 | St. James Park |
| Sat 15 Oct 1955 | BIRMINGHAM CITY | League | L 0-5 | Fratton Park |
| Sat 22 Oct 1955 | Charlton Athletic | League | L 1-6 | The Valley |
| Sat 29 Oct 1955 | TOTTENHAM HOTSPUR | League | W 4-1 | Fratton Park |
| Sat 05 Nov 1955 | Sheffield United | League | W 3-1 | Bramall Lane |
| Sat 12 Nov 1955 | PRESTON NORTH END | League | L 0-2 | Fratton Park |
| Sat 19 Nov 1955 | Burnley | League | L 0-3 | Turf Moor |
| Sat 26 Nov 1955 | LUTON TOWN | League | D 0-0 | Fratton Park |
| Sat 03 Dec 1955 | West Bromwich Albion | League | L 0-4 | The Hawthorns |
| Sat 10 Dec 1955 | MANCHESTER UNITED | League | W 3-2 | Fratton Park |
| Sat 17 Dec 1955 | HUDDERSFIELD TOWN | League | W 5-2 | Fratton Park |
| Sat 24 Dec 1955 | Blackpool | League | W 3-2 | Bloomfield Road |
| Mon 26 Dec 1955 | Aston Villa | League | W 3-1 | Villa Park |
| Tue 27 Dec 1955 | ASTON VILLA | League | D 2-2 | Fratton Park |
| Sat 31 Dec 1955 | CHELSEA | League | D 4-4 | Fratton Park |
| Mon 02 Jan 1956 | Manchester City | League | L 1-4 | Maine Road |
| Sat 14 Jan 1956 | Bolton Wanderers | League | L 0-4 | Burnden Park |
| Sat 21 Jan 1956 | ARSENAL | League | W 5-2 | Fratton Park |
| Sat 04 Feb 1956 | Everton | League | W 2-0 | Goodison Park |
| Sat 11 Feb 1956 | Sunderland | League | L 2-4 | Roker Park |
| Wed 22 Feb 1956 | NEWCASTLE UNITED | League | L 0-2 | Fratton Park |
| Sat 25 Feb 1956 | Birmingham City | League | L 2-3 | St. Andrews |
| Sat 03 Mar 1956 | BURNLEY | League | W 3-1 | Fratton Park |
| Sat 10 Mar 1956 | Tottenham Hotspur | League | D 1-1 | White Hart Lane |
| Sat 17 Mar 1956 | SHEFFIELD UNITED | League | D 1-1 | Fratton Park |
| Sat 24 Mar 1956 | Preston North End | League | L 1-2 | Deepdale |
| Fri 30 Mar 1956 | CARDIFF CITY | League | D 1-1 | Fratton Park |
| Sat 31 Mar 1956 | CHARLTON ATHLETIC | League | W 4-0 | Fratton Park |
| Mon 02 Apr 1956 | Cardiff City | League | W 3-2 | Ninian Park |
| Sat 07 Apr 1956 | Luton Town | League | L 0-1 | Kenilworth Road |
| Sat 14 Apr 1956 | WEST BROMWICH ALBION | League | D 1-1 | Fratton Park |
| Sat 21 Apr 1956 | Manchester United | League | L 0-1 | Old Trafford |
| Sat 28 Apr 1956 | MANCHESTER CITY | League | L 2-4 | Fratton Park |
